Quantitative rate determination by dynamic nuclear polarization enhanced NMR of a Diels-Alder reaction.

@article{Zeng2010QuantitativeRD,
  title={Quantitative rate determination by dynamic nuclear polarization enhanced NMR of a Diels-Alder reaction.},
  author={Haifeng Zeng and Youngbok Lee and Christian Hilty},
  journal={Analytical chemistry},
  year={2010},
  volume={82 21},
  pages={8897-902}
}
Emerging techniques for hyperpolarization of nuclear spins, foremost dynamic nuclear polarization (DNP), lend unprecedented sensitivity to nuclear magnetic resonance spectroscopy. Sufficient signal can be obtained from a single scan, and reactions even far from equilibrium can be studied in real-time. When following the progress of a reaction by nuclear magnetic resonance, however, spin relaxation occurs concomitantly with the reaction to alter resonance line intensities. Here, we present a… CONTINUE READING