Quantitative radioautographic study of intracellular localization of calmodulin antagonist, W-7, in Chinese-hamster ovary cells


The purpose of the present study was to analyse quantitatively the localization of calmodulin antagonist, n-(6-aminohexyl)-5-chloro-1-naphthalene-sulfonamide (W-7) in CHO-Kl cells. The cultured CHO-Kl cells were labelled with 1 (16.7 μM), 2 (33.4 μM), 5 (83.5 μM) and 10 μCi/ml (167 μM) tritiated W-7. Some cells were preincubated in 10, 50 and 100 μM… (More)
DOI: 10.1007/BF00502093


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