Quantitative proton MR spectroscopy findings in the corpus callosum of patients with schizophrenia suggest callosal disconnection.

@article{Aydin2007QuantitativePM,
  title={Quantitative proton MR spectroscopy findings in the corpus callosum of patients with schizophrenia suggest callosal disconnection.},
  author={Kubilay Aydin and Alp Uçok and Sibel Cakir},
  journal={AJNR. American journal of neuroradiology},
  year={2007},
  volume={28 10},
  pages={1968-74}
}
BACKGROUND AND PURPOSE The callosal disconnectivity theory was previously proposed to explain the pathophysiology of schizophrenia. The goal of this study was to investigate the metabolic integrity of the corpus callosum in patients with schizophrenia by proton MR spectroscopy. MATERIALS AND METHODS Twelve first-episode and 16 chronic patients meeting the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria for schizophrenia and 28 age- and sex-matched control subjects were… CONTINUE READING

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