Quantitative proteomics reveals that miR-155 regulates the PI3K-AKT pathway in diffuse large B-cell lymphoma.

@article{Huang2012QuantitativePR,
  title={Quantitative proteomics reveals that miR-155 regulates the PI3K-AKT pathway in diffuse large B-cell lymphoma.},
  author={Xin Huang and Yulei Shen and Miao Liu and Chengfeng Bi and Chunsun Jiang and Javeed Iqbal and T. Mckeithan and Wing Chung Chan and Shi-jian Ding and Kai Fu},
  journal={The American journal of pathology},
  year={2012},
  volume={181 1},
  pages={26-33}
}
The aberrant expression of microRNA-155 (miR-155), which has emerged as having a significant impact on the biological characteristics of lymphocytes, plays important roles in B-cell malignancies, such as diffuse large B-cell lymphoma (DLBCL). DLBCL is the most common non-Hodgkin's lymphoma in the adult population, accounting for approximately 40% of newly diagnosed non-Hodgkin's lymphoma cases globally. To determine the specific function of miR-155, a quantitative proteomics approach was… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 58 extracted citations

Similar Papers

Loading similar papers…