Quantitative proteomics reveals regulation of karyopherin subunit alpha-2 (KPNA2) and its potential novel cargo proteins in nonsmall cell lung cancer.

Abstract

The process of nucleocytoplasmic shuttling is mediated by karyopherins. Dysregulated expression of karyopherins may trigger oncogenesis through aberrant distribution of cargo proteins. Karyopherin subunit alpha-2 (KPNA2) was previously identified as a potential biomarker for nonsmall cell lung cancer by integration of the cancer cell secretome and tissue… (More)
DOI: 10.1074/mcp.M111.016592

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@article{Wang2012QuantitativePR, title={Quantitative proteomics reveals regulation of karyopherin subunit alpha-2 (KPNA2) and its potential novel cargo proteins in nonsmall cell lung cancer.}, author={Chun-I Wang and Kun-Yi Chien and Chih-Liang Wang and Hao-Ping Liu and Chia-Chen Cheng and Yu-sun Chang and J S Yu and Chia-Jung Yu}, journal={Molecular & cellular proteomics : MCP}, year={2012}, volume={11 11}, pages={1105-22} }