Quantitative proteomics reveals factors regulating RNA biology as dynamic targets of stress-induced SUMOylation in Arabidopsis.

@article{Miller2013QuantitativePR,
  title={Quantitative proteomics reveals factors regulating RNA biology as dynamic targets of stress-induced SUMOylation in Arabidopsis.},
  author={Marcus J. Miller and Mark A Scalf and Th{\'e}r{\`e}se C. Rytz and Shane L. Hubler and Lloyd M. Smith and Richard D Vierstra},
  journal={Molecular & cellular proteomics : MCP},
  year={2013},
  volume={12 2},
  pages={449-63}
}
The stress-induced attachment of small ubiquitin-like modifier (SUMO) to a diverse collection of nuclear proteins regulating chromatin architecture, transcription, and RNA biology has been implicated in protecting plants and animals against numerous environmental challenges. In order to better understand stress-induced SUMOylation, we combined stringent purification of SUMO conjugates with isobaric tag for relative and absolute quantification mass spectrometry and an advanced method to adjust… CONTINUE READING