Quantitative proteomics reveals differential biological processes in healthy neonatal cord neutrophils and adult neutrophils.

@article{Zhu2014QuantitativePR,
  title={Quantitative proteomics reveals differential biological processes in healthy neonatal cord neutrophils and adult neutrophils.},
  author={Jiang Zhu and Huoming Zhang and Tiannan Guo and Wenying Li and Huiyu Li and Yi Zhu and Shi'ang Huang},
  journal={Proteomics},
  year={2014},
  volume={14 13-14},
  pages={1688-97}
}
Neonatal neutrophils are characterized by the immaturity of bactericidal mechanisms that contributes largely to neonatal mortality. However, underlying molecular mechanism associated with the immaturity remains incompletely understood. In this study, we performed comparative proteomic analysis on neonatal neutrophils derived from human cord blood and adult peripheral neutrophils. A total of 1332 proteins were identified and quantified, and 127 proteins were characterized as differentially… CONTINUE READING