Quantitative proteomics for epigenetics.

  title={Quantitative proteomics for epigenetics.},
  author={Hans Christian Eberl and Matthias Mann and Michiel Vermeulen},
  journal={Chembiochem : a European journal of chemical biology},
  volume={12 2},
Mass spectrometry has made many contributions to the chromatin field through the mapping of histone modifications and the identification of protein complexes involved in gene regulation. MS-based proteomics has now evolved from the identification of single protein spots in gels to the identification and quantification of thousands of proteins in complex mixtures. Quantitative approaches also allow comparative and time-resolved analysis of post-translational modifications. An important emerging… CONTINUE READING

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