Quantitative proteomics by SWATH-MS reveals sophisticated metabolic reprogramming in hepatocellular carcinoma tissues

@article{Gao2017QuantitativePB,
  title={Quantitative proteomics by SWATH-MS reveals sophisticated metabolic reprogramming in hepatocellular carcinoma tissues},
  author={Yanyan Gao and Xinzheng Wang and Zhihong Sang and Zongcheng Li and F. Liu and Jie Mao and D. Yan and Yong-qiang Zhao and Hongli Wang and Ping Li and Xiaomin Ying and Xuemin Zhang and Kun He and Hongxia Wang},
  journal={Scientific Reports},
  year={2017},
  volume={7}
}
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and understanding its molecular pathogenesis is pivotal to managing this disease. Sequential window acquisition of all theoretical mass spectra (SWATH-MS) is an optimal proteomic strategy to seek crucial proteins involved in HCC development and progression. In this study, a quantitative proteomic study of tumour and adjacent non-tumour liver tissues was performed using a SWATH-MS strategy. In total, 4,216 proteins were… Expand
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