Quantitative proteomics analysis of detergent-resistant membranes from chemical synapses: evidence for cholesterol as spatial organizer of synaptic vesicle cycling.

@article{Jia2006QuantitativePA,
  title={Quantitative proteomics analysis of detergent-resistant membranes from chemical synapses: evidence for cholesterol as spatial organizer of synaptic vesicle cycling.},
  author={Jun-Yong Jia and Stephanie Lamer and M. Sch{\"u}mann and Michael R. Schmidt and Eberhard Krause and Volker Haucke},
  journal={Molecular & cellular proteomics : MCP},
  year={2006},
  volume={5 11},
  pages={2060-71}
}
Synaptic vesicles (SVs) in the central nervous system upon stimulation undergo rapid calcium-triggered exoendocytic cycling within the nerve terminal that at least in part depends on components of the clathrin- and dynamin-dependent endocytosis machinery. How exocytic SV fusion and endocytic retrieval are temporally and spatially coordinated is still an open question. One possibility is that specialized membrane microdomains characterized by their high content in membrane cholesterol may assist… CONTINUE READING

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Quantitative proteomics analysis of detergent - resistant membranes from chemical synapses : evidence for cholesterol as spatial organizer of synaptic vesicle cycling .
Quantitative proteomics analysis of detergent - resistant membranes from chemical synapses : evidence for cholesterol as spatial organizer of synaptic vesicle cycling .
Synaptic vesicles ( SVs ) in the central nervous system upon stimulation undergo rapid calcium - triggered exoendocytic cycling within the nerve terminal that at least in part depends on components of the clathrin- and dynamin - dependent endocytosis machinery .
Synaptic vesicles ( SVs ) in the central nervous system upon stimulation undergo rapid calcium - triggered exoendocytic cycling within the nerve terminal that at least in part depends on components of the clathrin- and dynamin - dependent endocytosis machinery .
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