Quantitative proteomic profiles of androgen receptor signaling in the liver of fathead minnows (Pimephales promelas).

@article{Martyniuk2009QuantitativePP,
  title={Quantitative proteomic profiles of androgen receptor signaling in the liver of fathead minnows (Pimephales promelas).},
  author={Christopher J. Martyniuk and Sophie Alvarez and Scott H. McClung and Daniel L. Villeneuve and Gerald T. Ankley and Nancy D. Denslow},
  journal={Journal of proteome research},
  year={2009},
  volume={8 5},
  pages={2186-200}
}
Androgenic chemicals are present in the environment at concentrations that impair reproductive processes in fish. The objective of this experiment was to identify proteins and cell processes mediated through androgen receptor signaling using an androgen receptor agonist (17beta-trenbolone) and antagonist (flutamide) in the liver. Female fathead minnows were exposed to nominal concentrations of either 17beta-trenbolone (0.05, 0.5, or 5 microg/L), flutamide (50, 150, or 500 microg/L), or a… CONTINUE READING

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2,000-gene microarray for the fathead minnow (Pimephales promelas)

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