Quantitative proteome analysis reveals annexin A3 as a novel biomarker in lung adenocarcinoma.

@article{Liu2009QuantitativePA,
  title={Quantitative proteome analysis reveals annexin A3 as a novel biomarker in lung adenocarcinoma.},
  author={Yicong Liu and Z Q Xiao and Ming Xing Li and Michael Yu Li and Peng Zhang and Chengwen Li and Fengyuan Li and Yu Husuan Chen and Hong Yi and H. X. Yao and Z Chen},
  journal={The Journal of pathology},
  year={2009},
  volume={217 1},
  pages={54-64}
}
Metastasis is a common phenomenon and the major lethal cause of lung adenocarcinoma (AdC). To discover novel potential biomarkers associated with lymph node metastasis and prognosis in lung AdC, we assessed differences in protein expression between primary lung AdC with (LNM AdC) and without lymph node metastasis (non-LNM AdC) using a quantitative proteomic approach. Laser capture microdissection was performed to purify the cancer cells from primary lung AdC tissues. The differential proteins… CONTINUE READING
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