Quantitative polymerase chain reaction: validation of microarray results from postmortem brain studies.

@article{Mimmack2004QuantitativePC,
  title={Quantitative polymerase chain reaction: validation of microarray results from postmortem brain studies.},
  author={Michael L Mimmack and Justin Brooking and Sabine Bahn},
  journal={Biological psychiatry},
  year={2004},
  volume={55 4},
  pages={337-45}
}
Quantitative polymerase chain reaction (Q-PCR) is now considered the "technique of choice" for validating gene expression changes identified with ribonucleic acid-based expression profiling technologies (especially micro- and macroarray techniques). The identification of altered gene expression profiles with microarrays is best viewed as the first step in the determination of potential disease-associated genes; however, the false-positive rate can be high, particularly with small sample sets… CONTINUE READING

From This Paper

Topics from this paper.
27 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

Similar Papers

Loading similar papers…