Quantitative organic acid analysis in cerebrospinal fluid and plasma: reference values in a pediatric population.

@article{Hoffmann1993QuantitativeOA,
  title={Quantitative organic acid analysis in cerebrospinal fluid and plasma: reference values in a pediatric population.},
  author={G. F. Hoffmann and Claudia K. Seppel and Beverly Holmes and Lisa N. Mitchell and Hans J{\"u}rgen Christen and Folker A Hanefeld and Dietz Rating and William L. Nyhan},
  journal={Journal of chromatography},
  year={1993},
  volume={617 1},
  pages={
          1-10
        }
}
Quantitative reference values for the concentrations of organic acids in cerebrospinal fluid (CSF) and plasma, as well as ratios of individual organic acids between CSF and plasma, were determined in twenty-three pairs of samples from pediatric patients. Twenty-six organic acids were present and quantifiable in all or the majority of plasma and CSF specimens (limit of detection 1 mumol/l). There were substantial differences between subgroups of organic acids, best reflected by the ratios of… CONTINUE READING

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