Quantitative neurohistological features of frontotemporal degeneration.

  title={Quantitative neurohistological features of frontotemporal degeneration.},
  author={Steven Edward Arnold and Liz Y. Han and C. M. Clark and Murray Grossman and John Q. Trojanowski},
  journal={Neurobiology of aging},
  volume={21 6},
Frontotemporal degeneration (FTD) is a neurodegenerative condition that has been principally associated with frontal lobe dementia. In this study, we compared neuropathological abnormalities in frontal, hippocampal, and calcarine cortices from patients assigned a diagnosis of FTD, normal elderly and Alzheimer's disease (AD). Densities of Nissl-stained neurons and lesions which were immunolabeled for tau, beta-amyloid (Abeta), alpha- and beta-synuclein, ubiquitin, glial fibrillary acidic protein… CONTINUE READING