Quantitative mass spectrometry-based assay development and validation: from small molecules to proteins.

@article{Boovi2013QuantitativeMS,
  title={Quantitative mass spectrometry-based assay development and validation: from small molecules to proteins.},
  author={Andrea Bo{\vz}ovi{\'c} and Vathany Kulasingam},
  journal={Clinical biochemistry},
  year={2013},
  volume={46 6},
  pages={444-55}
}
Mass spectrometry (MS) has emerged as a powerful analytical tool for the identification, characterization and quantification of various biomolecules (small molecules, drug metabolites and proteins) in biological specimens. The use of mass spectrometers in the clinical diagnostic laboratories have gained popularity due to its ease of development of new assays, ability to measure multiple analytes in a single analytical run, low volume requirements and low reagent costs. Novel technological… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 106 references

Mass spectrometry handbook

  • W Jian, W Shou, RW Edom, N Weng, M. Zhu
  • J Chromatogr A
  • 2012
1 Excerpt

Similar Papers

Loading similar papers…