Quantitative mapping of cerebral metabolic rate of oxygen (CMRO2 ) using quantitative susceptibility mapping (QSM).

@article{Zhang2015QuantitativeMO,
  title={Quantitative mapping of cerebral metabolic rate of oxygen (CMRO2 ) using quantitative susceptibility mapping (QSM).},
  author={Jingwei Zhang and Tian-kuan Liu and Ajay Gupta and Pascal Spincemaille and Thanh Dang Nguyen and Yi Wang},
  journal={Magnetic resonance in medicine},
  year={2015},
  volume={74 4},
  pages={945-52}
}
PURPOSE To quantitatively map cerebral metabolic rate of oxygen ( CMRO2) and oxygen extraction fraction ( OEF) in human brains using quantitative susceptibility mapping (QSM) and arterial spin labeling-measured cerebral blood flow (CBF) before and after caffeine vasoconstriction. METHODS Using the multiecho, three-dimensional gradient echo sequence and an oral bolus of 200 mg caffeine, whole brain CMRO2 and OEF were mapped at 3-mm isotropic resolution on 13 healthy subjects. The QSM-based… CONTINUE READING

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