Quantitative kinetic analysis of gene expression during human osteoblastic adhesion on orthopaedic materials.

@article{Rouahi2006QuantitativeKA,
  title={Quantitative kinetic analysis of gene expression during human osteoblastic adhesion on orthopaedic materials.},
  author={Myriam Rouahi and Eric Champion and Pierre Hardouin and Karine Anselme},
  journal={Biomaterials},
  year={2006},
  volume={27 14},
  pages={2829-44}
}
Little information was found in the literature about the expression on hydroxyapatite (HA) materials of genes specific of cellular adhesion molecules although more were found on titanium-based substrates. Hence, the goal of this work was to study by a kinetic approach from 30 min to 4 days the adhesion of Saos-2 cells on microporous (mHA) and non-microporous hydroxyapatite (pHA) in comparison to polished titanium. Our strategy associated the visualization of adhesion proteins inside the cells… CONTINUE READING