Quantitative investigation of murine cytomegalovirus nucleocapsid interaction.

  title={Quantitative investigation of murine cytomegalovirus nucleocapsid interaction.},
  author={Christopher Buser and F. Fleischer and Thomas Mertens and Detlef Michel and Volker Schmidt and Paul Walther},
  journal={Journal of microscopy},
  volume={228 Pt 1},
In this study, we quantitatively investigate the role of the M97 protein for viral morphogenesis in murine cytomegalovirus (MCMV)-infected fibroblast cells. For this purpose, a statistical analysis is performed for the spatial distribution of nuclear B-capsids (devoid of DNA, containing the scaffold) and C-capsids (filled with DNA). Cell nuclei infected with either wild-type or an M97 deletion mutant were compared. Univariate and multivariate point process characteristics (like Ripley's K… CONTINUE READING

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