Quantitative indexes of beta-cell function during graded up&down glucose infusion from C-peptide minimal models.

Abstract

Availability of quantitative indexes of insulin secretion is important for definition of the alterations in beta-cell responsivity to glucose associated with different physiopathological states. This is presently possible by using the intravenous glucose tolerance test (IVGTT) in conjunction with the C-peptide minimal model. However, the secretory response… (More)

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@article{Toffolo2001QuantitativeIO, title={Quantitative indexes of beta-cell function during graded up&down glucose infusion from C-peptide minimal models.}, author={Gianna Toffolo and Elena Breda and Melissa K. Cavaghan and Dominic Ehrmann and Kenneth S. Polonsky and Claudio Cobelli}, journal={American journal of physiology. Endocrinology and metabolism}, year={2001}, volume={280 1}, pages={E2-10} }