Quantitative immunocytochemical study of secretory protein expression in parotid glands of rats chronically treated with isoproterenol.

@article{Vugman1995QuantitativeIS,
  title={Quantitative immunocytochemical study of secretory protein expression in parotid glands of rats chronically treated with isoproterenol.},
  author={Ithamar Vugman and Arthur R Hand},
  journal={Microscopy research and technique},
  year={1995},
  volume={31 2},
  pages={106-17}
}
Chronic treatment of mice and rats with isoproterenol (IPR) causes marked hypertrophy and hyperplasia of the salivary glands, and alters the expression of several secretory proteins. We used quantitative postembedding immunogold labeling to study the cellular responses in the rat parotid gland during daily (up to 10 days) injections of IPR and during recovery (up to 14 days) after cessation of IPR treatment. Labeling densities of acinar cell secretory granules with antibodies to amylase and… CONTINUE READING
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