Quantitative imaging techniques for the assessment of osteoporosis and sarcopenia.

@article{Guerri2018QuantitativeIT,
  title={Quantitative imaging techniques for the assessment of osteoporosis and sarcopenia.},
  author={Sara Guerri and Daniele Mercatelli and Maria Pilar Aparisi G{\'o}mez and Alessandro Napoli and Giuseppe Battista and Giuseppe Guglielmi and Alberto Bazzocchi},
  journal={Quantitative imaging in medicine and surgery},
  year={2018},
  volume={8 1},
  pages={
          60-85
        }
}
Bone and muscle are two deeply interconnected organs and a strong relationship between them exists in their development and maintenance. The peak of both bone and muscle mass is achieved in early adulthood, followed by a progressive decline after the age of 40. The increase in life expectancy in developed countries resulted in an increase of degenerative diseases affecting the musculoskeletal system. Osteoporosis and sarcopenia represent a major cause of morbidity and mortality in the elderly… 

Figures from this paper

Diagnostic imaging of two related chronic diseases: Sarcopenia and Osteoporosis

The aim of this review is to present the different imaging modalities available for a non-invasive investigation of bone and muscle mass and quality in osteoporosis and sarcopenia, with their application and limitations.

Sarcopenia: imaging assessment and clinical application

The clinical implications of sarcopenia, how this condition can be assessed through different imaging modalities, and future perspectives of imaging of sarc Openia are reviewed.

Established paths and new avenues: a review of the main radiological techniques for investigating sarcopenia.

In an era pointing to the quantification and automatic evaluation of diseases, it is called for future research extending the application of organ tailored protocols, taking advantage of the most recent technical developments.

Imaging of sarcopenia: old evidence and new insights

DXA is an accurate, reproducible, and widely available imaging modality to evaluate body composition, being the most commonly used radiological tool to diagnose sarcopenia in clinical practice.

Sarcopenia: how to measure, when and why

An update of clinical knowledge about sarcopenia and advantages and limitations of radiological evaluation of sarc Openia focusing on major body composition imaging modalities such as dual-energy X-ray absorptiometry, CT, and MRI is presented.

Diagnosis of Osteosarcopenia – Imaging

This chapter explores the clinical applications and limitations of various imaging techniques available for the assessment of muscle and bone in the diagnosis of osteosarcopenia.

Recent Issues on Body Composition Imaging for Sarcopenia Evaluation

Controversial issues are discussed, including the lack of consensus and standardization of the disease definition, imaging modality, measurement methods, and diagnostic cutoff points.

Fat and bone: the multiperspective analysis of a close relationship.

What is the evidence on the physiological role of MAT in normal skeletal health (interaction with the other bone components), during the process of normal aging and in the context of some metabolic disorders, highlighting the role that imaging methods play in helping with quantification and diagnosis.

Associations of Muscle Size and Density With Proximal Femur Bone in a Community Dwelling Older Population

Positive associations of the gluteus and thigh muscle size with proximal femur volumetric BMD are observed, and thegluteus maximus muscle CSA was associated with trochanter cortical vBMD in both men and women.

Computed Tomography-Derived Skeletal Muscle Radiodensity Is an Early, Sensitive Marker of Age-Related Musculoskeletal Changes in Healthy Adults

L3SMD can be an early marker for age-related musculoskeletal changes showing linear decline throughout life from the second decade in healthy adults, with potential diagnostic value for individuals with low bone mass.
...

References

SHOWING 1-10 OF 230 REFERENCES

Integrated imaging approach to osteoporosis: state-of-the-art review and update.

New imaging modalities such as micro-CT and high-resolution magnetic resonance imaging have been developed in an attempt to help diagnose osteoporosis in its early stages, thereby reducing social and economic costs and preventing patient suffering.

Advances in bone imaging for osteoporosis

  • J. Adams
  • Medicine, Biology
    Nature Reviews Endocrinology
  • 2012
Improved reporting of radiographic features that suggest osteoporosis and the presence of vertebral fracture, which are powerful predictors of future fractures, could increase the frequency of appropriate DXA referrals.

Diagnostic imaging of two related chronic diseases: Sarcopenia and Osteoporosis

The aim of this review is to present the different imaging modalities available for a non-invasive investigation of bone and muscle mass and quality in osteoporosis and sarcopenia, with their application and limitations.

A review of the recent advances in magnetic resonance imaging in the assessment of osteoporosis

New techniques for assessing osteoporosis and predicting fracture risk are reviewed in this paper, including studies aimed at quantifying marrow relaxation times and establishing their relationship to trabecular bone density and structure.

Muscle analysis using pQCT, DXA and MRI.

Quantitative imaging methods in osteoporosis.

This review provides an overview of various quantitative imaging techniques based on different radiological modalities utilized in clinical osteoporosis care and research.

Magnetic resonance imaging for osteoporosis

Considerable effort is being expended in developing techniques to assess trabecular bone micro-architecture non-invasively, and magnetic resonance imaging techniques that serve as a surrogate for bone biopsies at multiple anatomic sites are used.

Quantitative ultrasound in the management of osteoporosis: the 2007 ISCD Official Positions.

  • M. KriegR. Barkmann D. Hans
  • Medicine
    Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry
  • 2008

Magnetic Resonance Imaging of Trabecular Bone Structure

  • S. Majumdar
  • Biology, Medicine
    Topics in magnetic resonance imaging : TMRI
  • 2002
3D, noninvasive imaging capabilities of magnetic resonance imaging (MRI) have been widely used clinically to assess and diagnose osteoporotic and vertebral fractures and can be used to assess the properties of trabecular bone in two different ways.

High-resolution imaging techniques for the assessment of osteoporosis.

...