Quantitative imaging techniques for the assessment of osteoporosis and sarcopenia.

@article{Guerri2018QuantitativeIT,
  title={Quantitative imaging techniques for the assessment of osteoporosis and sarcopenia.},
  author={Sara Guerri and Daniele Mercatelli and Maria Pilar Aparisi G{\'o}mez and Alessandro Napoli and Giuseppe Battista and Giuseppe Guglielmi and Alberto Bazzocchi},
  journal={Quantitative imaging in medicine and surgery},
  year={2018},
  volume={8 1},
  pages={
          60-85
        }
}
Bone and muscle are two deeply interconnected organs and a strong relationship between them exists in their development and maintenance. The peak of both bone and muscle mass is achieved in early adulthood, followed by a progressive decline after the age of 40. The increase in life expectancy in developed countries resulted in an increase of degenerative diseases affecting the musculoskeletal system. Osteoporosis and sarcopenia represent a major cause of morbidity and mortality in the elderly… 

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References

SHOWING 1-10 OF 230 REFERENCES
Integrated imaging approach to osteoporosis: state-of-the-art review and update.
TLDR
New imaging modalities such as micro-CT and high-resolution magnetic resonance imaging have been developed in an attempt to help diagnose osteoporosis in its early stages, thereby reducing social and economic costs and preventing patient suffering.
Advances in bone imaging for osteoporosis
  • J. Adams
  • Medicine, Biology
    Nature Reviews Endocrinology
  • 2012
TLDR
Improved reporting of radiographic features that suggest osteoporosis and the presence of vertebral fracture, which are powerful predictors of future fractures, could increase the frequency of appropriate DXA referrals.
Diagnostic imaging of two related chronic diseases: Sarcopenia and Osteoporosis
TLDR
The aim of this review is to present the different imaging modalities available for a non-invasive investigation of bone and muscle mass and quality in osteoporosis and sarcopenia, with their application and limitations.
A review of the recent advances in magnetic resonance imaging in the assessment of osteoporosis
TLDR
New techniques for assessing osteoporosis and predicting fracture risk are reviewed in this paper, including studies aimed at quantifying marrow relaxation times and establishing their relationship to trabecular bone density and structure.
Muscle analysis using pQCT, DXA and MRI.
Quantitative imaging methods in osteoporosis.
TLDR
This review provides an overview of various quantitative imaging techniques based on different radiological modalities utilized in clinical osteoporosis care and research.
Magnetic Resonance Imaging of Trabecular Bone Structure
  • S. Majumdar
  • Biology, Medicine
    Topics in magnetic resonance imaging : TMRI
  • 2002
TLDR
3D, noninvasive imaging capabilities of magnetic resonance imaging (MRI) have been widely used clinically to assess and diagnose osteoporotic and vertebral fractures and can be used to assess the properties of trabecular bone in two different ways.
High-resolution imaging techniques for the assessment of osteoporosis.
New advances in imaging osteoporosis and its complications
TLDR
Clinicians should aim to increase awareness of this fracture type both as a frequent and varied source of pain in patients with osteoporosis and as the ultimate marker of severely impaired bone strength.
Imaging of diabetic bone
TLDR
This paper is focused on imaging, covering different modalities involved in the evaluation of skeletal deterioration in diabetes, discussing the limitations of conventional methods and exploring the potential of new tools and recent high-resolution techniques to provide interesting insight into pathophysiology and fracture risk.
...
...