Quantitative genetic analysis of sleep in Drosophila melanogaster.

@article{Harbison2008QuantitativeGA,
  title={Quantitative genetic analysis of sleep in Drosophila melanogaster.},
  author={Susan T Harbison and Amita Sehgal},
  journal={Genetics},
  year={2008},
  volume={178 4},
  pages={
          2341-60
        }
}
Although intensively studied, the biological purpose of sleep is not known. To identify candidate genes affecting sleep, we assayed 136 isogenic P-element insertion lines of Drosophila melanogaster. Since sleep has been negatively correlated with energy reserves across taxa, we measured energy stores (whole-body protein, glycogen, and triglycerides) in these lines as well. Twenty-one insertions with known effects on physiology, development, and behavior affect 24-hr sleep time. Thirty-two… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-6 OF 6 REFERENCES

Molecular genetical analysis of Drosophila ether sensitive mutants

  • P. J. S haw
  • Toxicol . Lett .
  • 1998

Energy conservation and sleep

  • M. M.
  • Behav . Brain Res .
  • 1995

P - elementinduced variation in metabolic regulation in Drosophila

  • J. M. de C astro
  • Genetics
  • 1995

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