Quantitative fiber tracking of lateral and interhemispheric white matter systems in normal aging: relations to timed performance.

@article{Sullivan2010QuantitativeFT,
  title={Quantitative fiber tracking of lateral and interhemispheric white matter systems in normal aging: relations to timed performance.},
  author={Edith V. Sullivan and Torsten Rohlfing and Adolf Pfefferbaum},
  journal={Neurobiology of aging},
  year={2010},
  volume={31 3},
  pages={464-81}
}
The integrity of white matter, as measured in vivo with diffusion tensor imaging (DTI), is disrupted in normal aging. A current consensus is that in adults advancing age affects anterior brain regions disproportionately more than posterior regions; however, the mainstay of studies supporting this anterior-posterior gradient is based primarily on measures of the corpus callosum. Using our quantitative fiber tracking approach, we assessed fiber tract integrity of samples of major white matter… CONTINUE READING
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