Quantitative evaluation of partial deletions of the DAZ gene cluster.
@article{DAmico2006QuantitativeEO, title={Quantitative evaluation of partial deletions of the DAZ gene cluster.}, author={G. D'Amico and D. Di Benedetto and F. M. Pezzino and V. Giuffrida and M. Libra and M. Fichera and Grazia Mauceri and G. Rappazzo and R. D'agata and E. Vicari and S. Travali and A. Calogero}, journal={International journal of molecular medicine}, year={2006}, volume={17 5}, pages={ 785-9 } }
Partial deletions of the DAZ gene cluster are thought to cause spermatogenesis impairment. The presence of homologous copies of this gene in the Y chromosome does not allow PCR to be used for the identification of this abnormality. Hence, sequence family variants (SFV), following amplification of sY581, sY587 and sY586 and subsequent enzymatic digestion with Sau3A, DraI and TaqI, respectively, and the dual fiber fluorescence in situ hybridization (FISH) have been used to this aim. However, SFV… CONTINUE READING
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- Archives of andrology
- 2007
- 13
References
SHOWING 1-10 OF 23 REFERENCES
High frequency of DAZ1/DAZ2 gene deletions in patients with severe oligozoospermia.
- Biology, Medicine
- Molecular human reproduction
- 2002
- 168
- PDF
No partial DAZ deletions but frequent gene conversion events on the Y chromosome of fertile men
- Biology, Medicine
- Journal of Assisted Reproduction and Genetics
- 2005
- 12
Four DAZ genes in two clusters found in the AZFc region of the human Y chromosome.
- Biology, Medicine
- Genomics
- 2000
- 226
- PDF
Male infertility caused by a de novo partial deletion of the DAZ cluster on the Y chromosome.
- Biology, Medicine
- The Journal of clinical endocrinology and metabolism
- 2000
- 50
- PDF
AZF and DAZ gene copy-specific deletion analysis in maturation arrest and Sertoli cell-only syndrome.
- Biology, Medicine
- Molecular human reproduction
- 2004
- 45
- PDF
A large AZFc deletion removes DAZ3/DAZ4 and nearby genes from men in Y haplogroup N.
- Biology, Medicine
- American journal of human genetics
- 2004
- 187
Reduced copy number of DAZ genes in subfertile and infertile men.
- Biology, Medicine
- Fertility and sterility
- 2002
- 56
Polymorphic DAZ gene family in polymorphic structure of AZFc locus: Artwork or functional for human spermatogenesis?
- Biology, Medicine
- APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
- 2003
- 50
Analysis of the DAZ gene family in cryptorchidism and idiopathic male infertility.
- Biology, Medicine
- Fertility and sterility
- 2004
- 28
Y chromosome microdeletions and alterations of spermatogenesis.
- Biology, Medicine
- Endocrine reviews
- 2001
- 447
- PDF