Quantitative evaluation of focused ultrasound with a contrast agent on blood-brain barrier disruption.

@article{Yang2007QuantitativeEO,
  title={Quantitative evaluation of focused ultrasound with a contrast agent on blood-brain barrier disruption.},
  author={Feng-Yi Yang and Wen-Mei Fu and Rong-Sen Yang and H. L. Rachel Liou and K H Kang and Win-Li Lin},
  journal={Ultrasound in medicine & biology},
  year={2007},
  volume={33 9},
  pages={1421-7}
}
The use of an ultrasound contrast agent (UCA) with focused ultrasound sonication has the potential to disrupt the blood-brain barrier (BBB) noninvasively and reversibly at target locations. This study investigated the effects of UCA dose and ultrasound pressure on BBB disruption. Sonications were applied at 1 MHz with a burst length of 10 ms, a 1% duty… CONTINUE READING