Quantitative evaluation of cytomegalovirus DNA in infantile hepatitis.

  title={Quantitative evaluation of cytomegalovirus DNA in infantile hepatitis.},
  author={Tadao Funato and Naohiro Satou and Daiki Abukawa and Jun Satou and Yoshiko Abe and Keiko Ishii and Kazushige Iinuma and Mitsuo Kaku and Tomiya Sasaski},
  journal={Journal of viral hepatitis},
  volume={8 3},
We used a PCR method to develop a diagnostic assay for the detection of cytomegalovirus (CMV) DNA in infantile hepatitis, which has been suggested to be associated with CMV infection. CMV DNA was detected in 25 (58.1%) of 43 patients with elevated serum alanine aminotransferase (ALT) levels but no jaundice, and no hepatitis B or C as assessed by conventional PCR. None of the samples from 97 healthy infants tested positive for CMV DNA. We assayed CMV DNA quantitatively in blood using a real-time… CONTINUE READING