Quantitative evaluation of changes in the selected white matter tracts using diffusion tensor imaging in patients with Alzheimer's disease and mild cognitive impairment.

@article{Zimny2012QuantitativeEO,
  title={Quantitative evaluation of changes in the selected white matter tracts using diffusion tensor imaging in patients with Alzheimer's disease and mild cognitive impairment.},
  author={Anna Zimny and Paweł B. Szewczyk and Joanna Bladowska and Elżbieta Trypka and Renata Wojtyńska and Jerzy Leszek and Maria Sąsiadek},
  journal={The neuroradiology journal},
  year={2012},
  volume={25 3},
  pages={
          300-10
        }
}
This study evaluated the damage to the extensive range of white matter tracts in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI). Thirty-four patients with AD (mean age 71.5 yrs, MMSE 17.6), 23 patients with MCI (mean age 66 yrs, MMSE 27.4) and 15 normal controls (mean age 69 yrs, MMSE 29.8) were enrolled. Diffusion tensor imaging (DTI) was performed in 25 directions on 1.5 T MR scanner. Fractional anisotropy (FA) values were obtained with a small ROI method in… CONTINUE READING
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