Quantitative electron microscopy and fluorescence spectroscopy of the membrane distribution of influenza hemagglutinin

@article{Hess2005QuantitativeEM,
  title={Quantitative electron microscopy and fluorescence spectroscopy of the membrane distribution of influenza hemagglutinin},
  author={Samuel T. Hess and Mukesh Kumar and Anil Verma and Jane E Farrington and Anne K. Kenworthy and Joshua Zimmerberg},
  journal={The Journal of Cell Biology},
  year={2005},
  volume={169},
  pages={965 - 976}
}
Although lipid-dependent protein clustering in biomembranes mediates numerous functions, there is little consensus among membrane models on cluster organization or size. Here, we use influenza viral envelope protein hemagglutinin (HA(0)) to test the hypothesis that clustering results from proteins partitioning into preexisting, fluid-ordered "raft" domains, wherein they have a random distribution. Japan HA(0) expressed in fibroblasts was visualized by electron microscopy using immunogold… CONTINUE READING
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Fluorescence resonance energy transfer between single fluorophores attached to a coiled-coil protein in aqueous solution

  • Y. Ishii, T. Yoshida, T. Funatsu, T. Wazawa, T. Yanagida.
  • Chem. Phys. 247:163–173.
  • 1999
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