Quantitative dynamics of hepatitis B basal core promoter and precore mutants before and after HBeAg seroconversion.

Abstract

BACKGROUND & AIMS Hepatitis B e antigen (HBeAg) seroconversion is an important clinical and virological "landmark" during chronic hepatitis B virus (HBV) infection. Mutant viruses carrying the precore G1896A and/or the basal core promoter (BCP) A1762T/G1764A mutations are associated with HBeAg seroconversion. However, the exact role of these mutants in… (More)
DOI: 10.1016/j.jhep.2011.11.012

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