Quantitative determination of metabolic fluxes during coutilization of two carbon sources: comparative analyses with Corynebacterium glutamicum during growth on acetate and/or glucose.

@article{Wendisch2000QuantitativeDO,
  title={Quantitative determination of metabolic fluxes during coutilization of two carbon sources: comparative analyses with Corynebacterium glutamicum during growth on acetate and/or glucose.},
  author={Volker F Wendisch and Albert A. de Graaf and Hermann 4 Sahm and Bernhard J Eikmanns},
  journal={Journal of bacteriology},
  year={2000},
  volume={182 11},
  pages={
          3088-96
        }
}
Growth of Corynebacterium glutamicum on mixtures of the carbon sources glucose and acetate is shown to be distinct from growth on either substrate alone. The organism showed nondiauxic growth on media containing acetate-glucose mixtures and simultaneously metabolized these substrates. Compared to those for growth on acetate or glucose alone, the consumption rates of the individual substrates were reduced during acetate-glucose cometabolism, resulting in similar total carbon consumption rates… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-8 OF 8 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 55 REFERENCES

The era of pathway

  • D. E. Koshland, Jr.
  • quantification. Science
  • 1998

Similar Papers

Loading similar papers…