Quantitative determination of major active components in Ginkgo biloba dietary supplements by liquid chromatography/mass spectrometry.

@article{Ding2006QuantitativeDO,
  title={Quantitative determination of major active components in Ginkgo biloba dietary supplements by liquid chromatography/mass spectrometry.},
  author={Shujing Ding and Ed Dudley and Sue Plummer and Jiandong Tang and Russell P. Newton and A. Gareth Brenton},
  journal={Rapid communications in mass spectrometry : RCM},
  year={2006},
  volume={20 18},
  pages={2753-60}
}
A reversed-phase high-performance liquid chromatography/electrospray ionisation mass spectrometry (RP-HPLC/ESI-MS) method was developed and validated for the simultaneous determination of ten major active components in Ginkgo biloba extract (bilobalide, ginkgolides A, B, C, quercetin, kaempferol, isorhamnetin, rutin hydrate, quercetin-3-beta-D-glucoside and quercitrin hydrate) which have not been previously reported to be quantified in a single analysis. The ten components exhibit baseline… CONTINUE READING

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