Quantitative determination of chromophore concentrations from 2D photoacoustic images using a nonlinear model-based inversion scheme.

@article{Laufer2010QuantitativeDO,
  title={Quantitative determination of chromophore concentrations from 2D photoacoustic images using a nonlinear model-based inversion scheme.},
  author={Jan G. Laufer and Ben Cox and Edward Zhang and Paul C. Beard},
  journal={Applied optics},
  year={2010},
  volume={49 8},
  pages={1219-33}
}
A model-based inversion scheme was used to determine absolute chromophore concentrations from multiwavelength photoacoustic images. The inversion scheme incorporated a forward model, which predicted 2D images of the initial pressure distribution as a function of the spatial distribution of the chromophore concentrations. It comprised a multiwavelength diffusion based model of the light transport, a model of acoustic propagation and detection, and an image reconstruction algorithm. The model was… CONTINUE READING
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