Quantitative determination of bucindolol concentration in intact gel capsules using Raman spectroscopy.

@article{Niemczyk1998QuantitativeDO,
  title={Quantitative determination of bucindolol concentration in intact gel capsules using Raman spectroscopy.},
  author={Thomas M. Niemczyk and Miriam Delgado-Lopez and Felicity Allen},
  journal={Analytical chemistry},
  year={1998},
  volume={70 13},
  pages={2762-5}
}
The ideal quality control method for pharmaceutical products should be capable of rapid nondestructive testing of intact tablets or capsules. Raman spectroscopy using near-infrared excitation is shown to be capable of obtaining useful spectral data directly from drug formulations in gel capsules and from the gel capsules inside blister packs. The Raman data… CONTINUE READING