Quantitative characterization of pyrimidine dimer excision from UV-irradiated DNA (excision capacity) by cell-free extracts of the yeast Saccharomyces cerevisiae.

@article{Bekker1984QuantitativeCO,
  title={Quantitative characterization of pyrimidine dimer excision from UV-irradiated DNA (excision capacity) by cell-free extracts of the yeast Saccharomyces cerevisiae.},
  author={Morten Bekker and O. K. Kaboev and Alexander T. Akhmedov and Ludmila Luchkina},
  journal={FEBS letters},
  year={1984},
  volume={168 2},
  pages={245-8}
}
Cell-free extracts from wild-type yeast (RAD+) and from rad mutants belonging to the RAD3 epistatic group (rad1-1, rad2-1, rad3-1, rad4 -1) contain activities catalyzing the excision of pyrimidine dimers (PD) from purified ultraviolet-irradiated DNA which was not pre-treated with exogenous UV-endonuclease. The level of these activities in cell-free extracts… CONTINUE READING