Quantitative cerebral H2 15O perfusion PET without arterial blood sampling, a method based on washout rate

@article{Treyer2003QuantitativeCH,
  title={Quantitative cerebral H2 15O perfusion PET without arterial blood sampling, a method based on washout rate},
  author={Valerie Treyer and Mathieu Jobin and Cyrill Burger and Vincenzo Teneggi and Alfred Buck},
  journal={European Journal of Nuclear Medicine and Molecular Imaging},
  year={2003},
  volume={30},
  pages={572-580}
}
The quantitative determination of regional cerebral blood flow (rCBF) is important in certain clinical and research applications. The disadvantage of most quantitative methods using H2 15O positron emission tomography (PET) is the need for arterial blood sampling. In this study a new non-invasive method for rCBF quantification was evaluated. The method is based on the washout rate of H2 15O following intravenous injection. All results were obtained with Alpert's method, which yields maps of… CONTINUE READING

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