Quantitative bioluminescence tomography guided by diffuse optical tomography.

  title={Quantitative bioluminescence tomography guided by diffuse optical tomography.},
  author={Qizhi Zhang and Lu Ge Yin and Yiyong Tan and Zhen Yuan and Huabei Jiang},
  journal={Optics express},
  volume={16 3},
We present for the first time experimental evidence that the quantitative accuracy of bioluminescence tomography (BLT) can be significantly improved by incorporating prior spatial distribution of optical properties of heterogeneous media obtained from diffuse optical tomography (DOT). A series of experiments were conducted using a CCD-based scanning system where millimeter-size bioluminescent targets were embedded in a 3 x 3 x 5 cm optically heterogeneous scattering medium. The results show… CONTINUE READING
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