Quantitative bioimaging of platinum in polymer embedded mouse organs using laser ablation ICP-MS.

Abstract

A novel quantification approach for tissue imaging using laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) based on tissue embedding in cold-curing resins (Technovit 7100) is presented. With respect to massive side effects on cisplatin, the platinum distribution at different time intervals after cisplatin treatment of mice was… (More)
DOI: 10.1039/c3mt00147d

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