Quantitative assessment of the influence of PSMA6 variant (rs1048990) on coronary artery disease risk

@article{Wang2012QuantitativeAO,
  title={Quantitative assessment of the influence of PSMA6 variant (rs1048990) on coronary artery disease risk},
  author={Hairong Wang and Mei Jiang and Hua Zhu and Qihong Chen and Peihua Gong and Jie Lin and Jide Lu and Jianping Qiu},
  journal={Molecular Biology Reports},
  year={2012},
  volume={40},
  pages={1035-1041}
}
The proteasome system is a proteolytic pathway that regulates the expression of genes involved in inflammation. Recently, an association of a functional sequence variation, -8C/G, in the human proteasome subunit a type 6 gene (PSMA6) with the susceptibility to coronary artery disease (CAD) was reported. After that, several validation studies have been conducted among various ethnic populations, but the results have been inconsistent. To investigate this inconsistency and derive a more precise… CONTINUE READING
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