Quantitative assessment of regional alveolar ventilation and gas volume using 13N-N2 washout and PET.

@article{Richard2005QuantitativeAO,
  title={Quantitative assessment of regional alveolar ventilation and gas volume using 13N-N2 washout and PET.},
  author={J. C. Richard and Marc Janier and Franck Lavenne and Christian Tourvieille and Didier le Bars and Nicolas Costes and G{\'e}rard Gimenez and Claude Gu{\'e}rin},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2005},
  volume={46 8},
  pages={1375-83}
}
UNLABELLED Measurement of alveolar volume (Va) and regional ventilation (a) is crucial to understanding the pathophysiology of acute lung injury and ventilator-induced lung injury. PET has previously been used as a noninvasive, quantitative method to assess a, but formal validation of this technique in experimental lung injury is lacking. This study aims to validate Va and a regional assessment with PET, using inhaled (13)N-N(2) in pigs. METHODS Two normal and 2 oleic acid-injured pigs were… CONTINUE READING

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