Quantitative assessment of mammographic breast density: relationship with breast cancer risk.

@article{Harvey2004QuantitativeAO,
  title={Quantitative assessment of mammographic breast density: relationship with breast cancer risk.},
  author={Jennifer A. Harvey and Viktor E. Bovbjerg},
  journal={Radiology},
  year={2004},
  volume={230 1},
  pages={
          29-41
        }
}
Increased mammographic breast density is a moderate independent risk factor for breast cancer, with findings of published studies in which quantitative methods of assessment were used showing a positive association. Breast density may be quantified by using visual assessment or planimetry. Although the category definitions vary, the odds ratio for developing breast cancer for the most dense compared with the least dense breast tissue categories ranges from 1.8 to 6.0, with most studies yielding… 
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We investigated if associations of breast density and breast cancer differ according to the level of other known breast cancer risk factors, including body mass index (BMI), age at menarche, parity,…
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    The British journal of radiology
  • 2011
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Findings on associations by menopausal status/hormone use are suggestive and should be examined in additional larger studies.
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Mammographic Breast Density and Subsequent Risk of Breast Cancer in Postmenopausal Women According to the Time Since the Mammogram
TLDR
Patterns of the associations between percent density, absolute dense, and nondense area with breast cancer risk persist for up to 10 years after the mammogram, suggesting a one-time density measure can be used for long-term breastcancer risk prediction.
Mammographic density: use in risk assessment and as a biomarker in prevention trials.
TLDR
There is no current evidence that change in breast density alters individual breast cancer risk, and more studies are needed that examine the comparative discriminatory ability of mammographic density or nondiagnostic tissue sampling when added to the Gail or other epidemiologic risk models.
Breast density measurements using ultrasound tomography for patients undergoing tamoxifen treatment
TLDR
Initial results of UST examinations of tamoxifen treated patients show that approximately 45% of the patients have a decrease in density in the contralateral breast after only several months of treatment, suggesting that UST may enable rapid assessment of density changes associated with therapeutic and preventative interventions.
Mammographic breast density and subsequent risk of breast cancer in postmenopausal women according to tumor characteristics.
TLDR
The findings suggest that higher mammographic density is associated with more aggressive tumor characteristics and also with in situ tumors.
Varying Levels of Family History of Breast Cancer in Relation to Mammographic Breast Density (United States)
TLDR
Having a family history of breast cancer was more strongly associated with mammographic breast density when the affected relatives were more genetically similar.
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