Quantitative assessment of glioblastoma invasion in vivo.

The aim of this study was the quantitative assessment of the time course and spatial distribution in brain of invading glioblastoma (GBM) cells using a recently described model consisting of RT2 rat GBM cells stably transfected with enhanced green fluorescent protein (eGFP) - called RT2-eGFP - and implanted in Fischer rats. Invasion throughout the brain was… (More)