Quantitative assessment of Fc receptor expression and function during in vitro differentiation of human monocytes to macrophages.


The expression and function of IgG Fc receptors on peripheral blood monocytes and monocytes differentiating in vitro, within hydrophobic membranes, to macrophages have been determined. Three characteristic functional stages could be discerned, and these were reflected in the surface expression of specific IgG binding sites. Stage 1, represented by fresh… (More)


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