Quantitative analysis of xanthohumol and related prenylflavonoids in hops and beer by liquid chromatography-tandem mass spectrometry.

@article{Stevens1999QuantitativeAO,
  title={Quantitative analysis of xanthohumol and related prenylflavonoids in hops and beer by liquid chromatography-tandem mass spectrometry.},
  author={J. Frederik Stevens and A. Wormald Taylor and Max L. Deinzer},
  journal={Journal of chromatography. A},
  year={1999},
  volume={832 1-2},
  pages={
          97-107
        }
}
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274 Citations
Highly Influential Citations
18
Background Citations
75
Methods Citations
17
Results Citations
6

274 Citations

Evaluation of prenylflavonoids and hop bitter acids in surplus yeast
TLDR
The positive mode was discovered to possess satisfactory collision capacity and high sensitivity for prenylflavonoids, while the negative mode was more suitable for the ionization of hop bitter acids.
Quantitation of 8-prenylnaringenin, a novel phytoestrogen in hops (Humulus lupulus L.), hop products, and beers, by benchtop HPLC-MS using electrospray ionization
Summary8-Prenylnaringenin (8-PN), a potent phytoestrogen, present in hops (Humulus lupulus L.), hop products, and most beers, exhibits an estrogenic activity greater than that of any of the known…
Analytical condition setting a crucial step in the quantification of unstable polyphenols in acidic conditions: analyzing prenylflavanoids in biological samples by liquid chromatography-electrospray ionization triple quadruple mass spectrometry.
TLDR
It was concluded that a neutral pH (pH 7.0) is necessary for the analysis of prenylflavanoids, in order to maintain the stability of compounds for at least 24 h.
Simultaneous determination of prenylflavonoid and hop bitter acid in beer lee by HPLC-DAD-MS.
Analysis of xanthohumol and isoxanthohumol in different hop products by liquid chromatography-diode array detection-electrospray ionization tandem mass spectrometry.
Fast Screening Method to Determine Hop’s Phytoestrogens in Beer
A novel, fast, and simple method to determine three phytoestrogens [xanthohumol (XN), isoxanthohumol (IXN), and 8-prenylnaringenin (8PN)] in beer samples by high-performance liquid chromatography…
Characterization of the methanolic extract of hops using capillary electrophoresis‐electrospray ionization‐mass spectrometry
TLDR
The optimization of CZE parameters (pH, concentration, and type of buffer) and ESI‐MS parameters have permitted the development of a rapid, simple, direct, and straightforward CZE–ESI‐MS method for the identification of components of methanolic extracts from different hops used in the brewing process.
Determination of resveratrol and piceid in beer matrices by solid-phase extraction and liquid chromatography-tandem mass spectrometry.
Enantiospecific analysis of 8-prenylnaringenin in biological fluids by liquid-chromatography-electrospray ionization mass spectrometry: application to preclinical pharmacokinetic investigations.
TLDR
A novel and simple liquid chromatographic-electrospray ionization-mass spectrometry (LC-ESI-MS) method was developed and successfully validated showing that it was sensitive, reproducible, and accurate for enantiospecific quantification of 8PN in biological matrices.
Characterization of prenylflavonoids and hop bitter acids in various classes of Czech beers and hop extracts using high-performance liquid chromatography-mass spectrometry.
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References

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Synthesis of (±) lupinifoun, di-o-methyl xanthohumol and isoxanthohumol and related compounds
Prenylflavonoids from Humulus lupulus
Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands
The content of the potentially anticarcinogenic flavonoids quercetin, kaempferol, myricetin, apigenin, and luteolin of 28 vegetables and 9 fruits was determined by RP-HPLC with UVdetection. Fresh…
Isoprenylated flavonoids—a survey
Analysis of plasma isoflavones by reversed-phase HPLC-multiple reaction ion monitoring-mass spectrometry.
A microbore high performance liquid chromatography/electrospray ionization mass spectrometry method for the determination of the phytoestrogens genistein and daidzein in comminuted baby foods and soya flour.
TLDR
The microbore high performance liquid chromatographic/electrospray/mass spectrometric method developed for the determination of the phytoestrogens daidzein and genistein in soya flours and baby foods proved both robust and reliable when operated over a long time period.