Quantitative analysis of tau protein-immunoreactive accumulations and β amyloid protein deposits in the cerebral cortex of the mouse lemur, Microcebus murinus

@article{Giannakopoulos1997QuantitativeAO,
  title={Quantitative analysis of tau protein-immunoreactive accumulations and β amyloid protein deposits in the cerebral cortex of the mouse lemur, Microcebus murinus},
  author={Panteleimon Giannakopoulos and S. Silhol and V. Jallageas and Jacques Mallet and N. Bons and Constantin Bouras and Pia Dela{\`e}re},
  journal={Acta Neuropathologica},
  year={1997},
  volume={94},
  pages={131-139}
}
Recent studies have revealed the presence of tau protein-immunoreactive accumulations and β amyloid protein (Aβ) deposits in the cerebral cortex of the aged mouse lemur, Microcebus murinus. To examine the age-related evolution of these changes and compare their regional distribution to that reported for humans and nonhuman primates with Alzheimer’s disease lesions, we performed a quantitative analysis of a large series of mouse lemurs aged from 1 to 13 years. The prevalence and density of tau… CONTINUE READING

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