Quantitative analysis of syndecan-1 expression in dysplasia and squamous cell carcinoma of the oral cavity.

@article{Jackson2007QuantitativeAO,
  title={Quantitative analysis of syndecan-1 expression in dysplasia and squamous cell carcinoma of the oral cavity.},
  author={Lana L Jackson and Zane K Wade and Richard B. Hessler and Rafik A Abdelsayed and Jeremy Rogers and Christine G Gourin},
  journal={The Laryngoscope},
  year={2007},
  volume={117 5},
  pages={868-71}
}
INTRODUCTION Decreased expression of syndecan-1 has been reported in dysplasia and squamous cell carcinoma (SCCA) of the oral cavity and appears to correlate with decreasing histological differentiation and poor clinical outcome. Assays of syndecan-1 expression to date have utilized manual microscopic analysis with qualitative grading of immunohistochemical staining intensity, which may introduce observer bias. We evaluated syndecan-1 expression in dysplasia and squamous cell carcinoma (SCCA… CONTINUE READING

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