Quantitative analysis of gene expression in a rabbit model of intervertebral disc degeneration by real-time polymerase chain reaction.

@article{Sobajima2005QuantitativeAO,
  title={Quantitative analysis of gene expression in a rabbit model of intervertebral disc degeneration by real-time polymerase chain reaction.},
  author={Satoshi Sobajima and Adam L. Shimer and Robert C Chadderdon and John F Kompel and Joseph S Kim and Lars G. Gilbertson and James D. Kang},
  journal={The spine journal : official journal of the North American Spine Society},
  year={2005},
  volume={5 1},
  pages={14-23}
}
BACKGROUND CONTEXT Serial analysis of gene expression during the course of intervertebral disc degeneration (IDD) could elucidate valuable insight into pathophysiology and provide a basis for identification of potential targets for the development of novel cellular- and gene-based therapies. However, very few previous studies described the changes in gene expression through the process of IDD using a suitable animal model. PURPOSE To use a recently developed rabbit annular stab model and the… CONTINUE READING

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