Quantitative analysis of coronary endothelial function with generator-produced 82Rb PET: comparison with 15O-labelled water PET

@article{Yoshinaga2010QuantitativeAO,
  title={Quantitative analysis of coronary endothelial function with generator-produced 82Rb PET: comparison with 15O-labelled water PET},
  author={Keiichiro Yoshinaga and Osamu Manabe and Chietsugu Katoh and Li Chen and Ran Klein and Masanao Naya and Robert A. deKemp and Kathryn Williams and Rob S. B. Beanlands and N. Tamaki},
  journal={European Journal of Nuclear Medicine and Molecular Imaging},
  year={2010},
  volume={37},
  pages={2233-2241}
}
Endothelial dysfunction is the earliest abnormality in the development of coronary atherosclerosis. 82Rb is a generator-produced positron emission tomography (PET) myocardial perfusion tracer that is becoming more widely used. We aimed to (1) develop a method for quantitative assessment of coronary endothelial function using the myocardial blood flow (MBF) response during a cold pressor test (CPT) in smokers, measured using 82Rb PET, and (2) compare the results with those measured using 15O… CONTINUE READING

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