Quantitative analysis of basic fibroblast growth factor and vascular endothelial growth factor in human colorectal cancer.

@article{Landriscina1998QuantitativeAO,
  title={Quantitative analysis of basic fibroblast growth factor and vascular endothelial growth factor in human colorectal cancer.},
  author={Matteo Landriscina and Alessandra Cassano and Carlo Ratto and Roberta Longo and Micaela Ippoliti and Bernardetta Palazzotti and Francesco Crucitti and Carlo Barone},
  journal={British Journal of Cancer},
  year={1998},
  volume={78},
  pages={765 - 770}
}
Tumour growth is angiogenesis dependent. Some authors suggest a prognostic role of microvessel count in colorectal cancer. We tested the role of basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) in the switch to the angiogenic phenotype in 35 patients with colorectal cancer at different stages of disease. We evaluated the two angiogenic factors, by enzyme-linked immunosorbent assay (ELISA), in tumour, peritumoral mucosa, pathological mesenteric and peripheral… CONTINUE READING

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