Quantitative analyses of variations in the injury of endothelial cells elicited by 11 isolates of Rickettsia rickettsii.

@article{Eremeeva2001QuantitativeAO,
  title={Quantitative analyses of variations in the injury of endothelial cells elicited by 11 isolates of Rickettsia rickettsii.},
  author={Marina E. Eremeeva and Gregory A. Dasch Gregory A. Dasch and David J. Silverman},
  journal={Clinical and diagnostic laboratory immunology},
  year={2001},
  volume={8 4},
  pages={788-96}
}
Eleven isolates of spotted fever group rickettsiae from the blood of patients or ixodid ticks from North and South America were characterized. All isolates were identified as Rickettsia rickettsii using restriction fragment length polymorphism analysis of a 532-bp rOmpA gene fragment obtained by PCR. The ability of the R. rickettsii isolates to elicit cytopathic effects and parameters of oxidative injury were examined in cultured human EA.hy 926 endothelial cells. Cytopathic effects were… CONTINUE READING